Fonti di Proteine, Compromessi tra Animale e Vegetale, e Salute a Lungo Termine
La fonte delle proteine alimentari, non solo la quantità, sembra avere conseguenze significative per l'invecchiamento, la salute metabolica e il rischio di malattia. Dalla segnalazione dell'IGF-1 alla colina derivata dalle uova e ai contaminanti negli integratori proteici, le evidenze suggeriscono che il modo in cui le proteine vengono scelte e preparate conta considerevolmente.
Creato con l'IALe proteine alimentari vengono raramente discusse con la sfumatura che meritano. La maggior parte delle conversazioni si concentra su quante proteine mangiare, eppure un numero crescente di evidenze suggerisce che la fonte di quelle proteine, la loro composizione in aminoacidi, il modo in cui vengono processate e persino il modo in cui vengono cotte possano avere conseguenze che vanno ben oltre la massa muscolare. Comprendere queste distinzioni può orientare scelte alimentari più precise, sebbene la variabilità individuale, le differenze di qualità degli alimenti tra le regioni e la complessità delle diete reali significhino che nessuna prescrizione unica sia adatta a tutti.
Creato con l'IAProteine Animali, IGF-1 e Segnali di Longevità
Una delle distinzioni più rilevanti tra proteine animali e vegetali risiede nel modo in cui ciascuna influenza le vie di segnalazione della crescita nell'organismo. Secondo il Dr. Valter Longo, scienziato della longevità presso l'USC, le proteine animali sono più ricche di leucina, metionina e aminoacidi a catena ramificata, gli aminoacidi specifici che attivano più potentemente l'IGF-1 e il suo bersaglio a valle, mTOR. L'attività cronicamente elevata di IGF-1 e mTOR è associata all'invecchiamento cellulare accelerato e a un maggiore rischio di cancro, secondo Longo, perché queste vie promuovono la crescita cellulare e sopprimono i processi di manutenzione cellulare che proteggono la salute a lungo termine.
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