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Hormones & Women's Health1 min read

How Cortisol Drives Visceral Fat Accumulation and What Sustains the Cycle

Chronic cortisol elevation preferentially deposits fat around the organs through mechanisms that go well beyond simple caloric surplus. Understanding the receptor biology, the local tissue enzyme activity, and the feedback loops that keep the system stuck is essential for addressing visceral fat accumulation at its root.

Wie Cortisol die Ansammlung von viszeralem Fett antreibt und was den Kreislauf aufrechthältCreated with AI

Visceral fat, the fat stored around the abdominal organs rather than beneath the skin, carries a distinct metabolic profile compared to subcutaneous fat. Its accumulation is not simply a consequence of eating too much; it is, in large part, a hormonal and inflammatory phenomenon in which cortisol plays a central organizing role. Grasping why cortisol targets this particular fat depot, and why the system can become self-sustaining, changes how the problem needs to be approached.

Why Visceral Fat Is Especially Sensitive to CortisolCreated with AI

Why Visceral Fat Is Especially Sensitive to Cortisol

The preferential accumulation of fat in the visceral depot under conditions of chronic stress has a clear receptor-level explanation. According to Dr. Michael Diamonds, visceral fat contains a higher concentration of glucocorticoid receptors than subcutaneous fat. Because cortisol binds to glucocorticoid receptors to exert its effects, the visceral depot is disproportionately responsive to circulating cortisol. The practical consequence is that even modest or intermittent elevations in cortisol, if sustained over time, will drive fat storage preferentially around the organs rather than elsewhere in the body.

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